RSNA2013「オススメ演題」について
山口 健先生（佐賀大学）にお答えいただきました。
CODE:LL-BRS-SU2B
Scientific informal presentations
Microcalcifications in 1,658 Patients with Pure Ductal Carcinoma in Situ of the Breast: Imaging Findings with Clinical,
Histopathologic and Biologic Correlation
Gaiane M Rauch, et al.
DATE:Sunday, December 1st 2013
TIME:01:00 PM – 01:30 PM
LOCATION:Lakeside Learning Center
PURPOSE:
Analyze microcalcifications (MC) on mammography (M) in patients with pure ductal carcinoma in situ (DCIS) by nuclear grade (G), comedonecrosis (CN), estrogen receptor (ER) status, patient age and surgical outcome.
【コメント】
1658例というかなり多数の非浸潤性乳管癌症例を用いてその病理組織学的所見あるいは臨床所見と画像所見との関連を検討した報告。
CODE:LL-BRS-MO3A
Scientific informal presentations
Imaging Lymphatic System in Breast Cancer Patients with Magnetic Resonance Lymphangiography
Qing Lu, et al.
DATE:Monday, December 2nd 2013
TIME:12:15 PM – 12:45 PM
LOCATION:Lakeside Learning Center
PURPOSE:
To investigate the feasibility of magnetic resonance lymphangiography (MRL) protocol using a gadolinium (Gd)-based contrast agent (Gd-MRL) for breast patients in a typical clinical setting, and to establish a Gd-MRL protocol and identify potential MRL biomarkers for differentiating metastatic from non-metastatic lymph nodes.
【コメント】
腋窩リンパ節転移に対するガドリニウム造影剤を用いたMRIでのリンパ管造影の有用性を検討した報告。
CODE:SSE01-03
Scientific formal presentations
Can Breast Cancer Molecular Subtype Help Select Patients for Preoperative MRI?
Lars J Grimm, et al.
DATE:Monday, December 2nd 2013
TIME:03:20 PM – 03:30 PM
LOCATION:Arie Crown Theater
PURPOSE:
To determine whether breast cancer molecular subtype can help predict which patients will benefit from preoperative breast MRI.
【コメント】
乳癌Molecular subtypeと術前MRIで治療方針に関与する所見との関連を検討した報告。Luminal B typeやHER2 typeは他のtypeに比べmulticentric/multifocalであり、さらにLuminal B typeは他のtypeよりリンパ節浸潤が多いと結論しています。
CODE:SSE01-06
Scientific formal presentations
Prepectoral Edema as a Morphological Sign in MR-mammography
Clemens G Kaiser, et al.
DATE:Monday, December 2nd 2013
TIME:03:50 PM – 04:00 PM
LOCATION:Arie Crown Theater
PURPOSE:
Morphological and kinetic signs of breast lesions contribute to diagnosis and differential diagnosis in MR-Mammography. Prepectoral edema in patients without any history of previous biopsy, operation, radiation or chemotherapy has been detected as a new diagnostic Sign during clinical routine. The purpose of this study was to evaluate the role of this morphological sign in the differential diagnosis of breast lesions.
【コメント】
乳腺MRIで見られる胸筋前方の浮腫と乳腺疾患との関連を検討した報告。浮腫は乳癌の特に低分化度やリンパ節転移などと関連があり、予後不良因子と結論しています。
CODE:LL-BRS-TU1B
Scientific informal presentations
MR Imaging of Breast before and after Neoadjuvant Chemotherapy: Does Breast Parenchymal Enhancement in the Contralateral Normal Breast Change after Chemotherapy?
Akiko Shimauchi, et al.
DATE:Tuesday, December 3rd 2013
TIME:12:45 PM – 01:15 PM
LOCATION:Lakeside Learning Center
PURPOSE:
To investigate the change of breast parenchymal enhancement (BPE) on MRI, in the contralateral normal breast of patients who received neoadjuvant chemotherapy (NAC) for breast cancer.
【コメント】
乳癌の化学療法前後での背景乳腺の濃染の程度を評価した報告。化学療法後では前にくらべ濃染の程度が低下すると結論しています。
CODE:LL-BRS-TU7B
Scientific informal presentations
Breast Cancer Staging: Comparison of Whole-body Hybrid MR/PET and PET/CT Imaging: Initial Experience
Onofrio A Catalano, et al.
DATE:Tuesday, December 3rd 2013
TIME:12:45 PM – 01:15 PM
LOCATION:Lakeside Learning Center
PURPOSE:
To compare the diagnostic staging performance and SUV measurement accuracy of whole-body hybrid MR/ PET with PET/CT in patients with breast cancer.
【コメント】
乳癌のstagingとPETでのSUVに関して全身PET-MRIとPET-CTを比較した報告。
CODE:SSJ01-02
Scientific formal presentations
The Relationship of Breast Density in Mammography and Magnetic Resonance (MR) Imaging in Women at High Risk for
Developing Breast Cancer and Women with Breast Cancer
Freya Schnabel, et al.
DATE:Tuesday, December 3rd 2013
TIME:03:10 PM – 03:20 PM
LOCATION:Arie Crown Theater
PURPOSE:
Mammographic breast density (BD) is associated with a 4 to 6-fold increased risk for developing breast cancer. Background parenchymal enhancement (BPE) in MRI has also been correlated with breast cancer risk. The purpose of our study was to evaluate the relationship between BD, BPE, and FGT (assessment of fibroglandular tissue with contiguous MR images) in women with breast cancer (BC) and at high risk (HR) for developing breast cancer.
【コメント】
マンモグラフィーでの乳腺濃度やMRIでの背景乳腺の濃染、線維腺組織の程度と乳癌との関連を検討した報告。これらの因子は乳癌家族歴や遺伝子異常などをもった乳癌ハイリスクグループに比べて乳癌の発症率が高く乳癌のリスクファクターであると結論しています。
CODE:SSK02-06
Scientific formal presentations
Cancer Detection Rate on Short-term, as well as Long-term Follow-up MRI after a Benign Concordant MRI-guided Breast Biopsy
Elana I Den, et al.
DATE:Wednesday, December 4th 2013
TIME:11:20 AM – 11:30 AM
LOCATION:E450A
PURPOSE:
To determine the cancer detection rate on short-term and long-term follow-up MRI after a benign concordant MRI-guided breast biopsy.
【コメント】
MRガイド下生検で良性と診断された症例に対するMRIを用いた短期及び長期経過観察の結果の検討。生検後のMRIによる経過観察で新たに指摘された乳癌はわずかに0.6%で、良性と診断された症例に対するMRIによる経過観察の有用性は低いと結論しています。
CODE:LL-BRS-WE4B
Scientific informal presentations
MRI-Detected Additional Suspicious Lesions in Breast Cancer Patients: Probability of Malignancy according to Molecular
Subtypes of Index Tumors
So Yoon Park, et al.
DATE:Wednesday, December 4th 2013
TIME:12:45 PM – 01:15 PM
LOCATION:Lakeside Learning Center
PURPOSE:
To evaluate the difference of the incidence and the probability of malignancy of MRI-detected additional suspicious lesions in breast cancer patients according to the molecular subtype of index tumor.
【コメント】
乳癌患者のMR偶発病変とindex lesionのmolecular subtypeとの関連を検討した報告。Index lesionがtriple-negative cancerの場合、MR偶発病変が悪性である率は他のsubtypeより低いと結論しています。
CODE:SSM01-05
Scientific formal presentations
Invasive Breast Cancer MRI Phenotype and Receptor Status as Predictors of Clinical Outcome
Kirti M Kulkarni, et al.
DATE:Wednesday, December 4th 2013
TIME:03:40 PM – 03:50 PM
LOCATION:Arie Crown Theater
PURPOSE:
Can aggressive MRI characteristics and receptor profile of invasive breast cancers be used to predict clinical outcome and metastases/recurrence rates?
【コメント】
乳癌のMRIでの性状やレセプター発現の有無が転移、再発などの臨床的な予後の予測に有用かどうかを検討した報告。Triple-negative cancerやMRI上非腫瘤性の形状を呈するもの、MRI上多発する浸潤性乳管癌は他に比べ転移する率が高いと結論しています。
CODE:SSM01-06
Scientific formal presentations
MR Imaging Phenotype of Breast Cancer: Kinetic Assessment for Molecular Subtypes
Eric M Blaschke, et al.
DATE:Wednesday, December 4th 2013
TIME:03:50 PM – 04:00 PM
LOCATION:Arie Crown Theater
PURPOSE:
To evaluate the dynamic contrast enhanced MR kinetic characteristics of newly diagnosed breast cancer in molecular subtypes.
【コメント】
乳癌のMRIでの血流動態のパターンとmolecular subtypeとの関連を検討した報告。HER2 typeは他のtypeに比べて早期相でのrapid uptakeを呈する率が高いと結論しています。
